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Saikosaponin-D Alleviates Renal Inflammation and Cell Apoptosis in a Mouse Model of Sepsis via TCF7/FOSL1/MMP9 Inhibition
Molecular and Cellular Biology ( IF 3.2 ) Pub Date : 2021-07-26 , DOI: 10.1128/mcb.00332-21
Tao Yao 1 , Lei Zhang 1 , Ye Fu 1 , Lina Yao 1 , Chengjie Zhou 1 , Guozhong Chen 1
Affiliation  

Evidence exists reporting that Saikosaponin-d can prevent experimental sepsis, and this study aims to illustrate the molecular events underlying its renoprotective effects on lipopolysaccharide (LPS)-induced renal inflammation simulating sepsis. Through ...

中文翻译:

Saikosaponin-D 通过 TCF7/FOSL1/MMP9 抑制减轻脓毒症小鼠模型中的肾脏炎症和细胞凋亡

有证据表明 Saikosaponin-d 可以预防实验性败血症,本研究旨在说明其对脂多糖 (LPS) 诱导的模拟败血症的肾脏炎症的肾脏保护作用的分子事件。通过 ...
更新日期:2021-09-12
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