Retraction Note: Small interfering RNA targeted to stem-loop II of the 5′ untranslated region effectively inhibits expression of six HCV genotypes,Virology Journal

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Retraction Note: Small interfering RNA targeted to stem-loop II of the 5′ untranslated region effectively inhibits expression of six HCV genotypes
Virology Journal ( IF 4.0 ) Pub Date : 2021-07-26 , DOI: 10.1186/s12985-021-01623-y
Ramesh Prabhu ₁ , Robert F Garry ₂ , Srikanta Dash ₁

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The Editor-in-Chief has retracted this article. Concerns were raised regarding a number of figures, specifically:

Figure 4: the pCVH77C/+siRNA74 panel appears to overlap with the pCVJ4L6S/+siRNA74 panel
Figure 4: the pCVH77C/Full-length HCV panel appears to be identical with the pM.O.9.6.-T7/+EBNA1 panel
Figure 6: the bottom center and bottom right panels appear to be identical

The article also shows significant overlap with a previously published article [1]. The Editor-in-Chief therefore no longer has full confidence in the reliability of some data reported in the article.

Robert F. Garry and Srikanta Dash agree to this retraction. The editor was not able to obtain a current email address for Ramesh Prabhu.

1.
Prabhu R, Vittal P, Yin Q, Flemington E, Garry R, Robichaux WH, Dash S. Small interfering RNA effectively inhibits protein expression and negative strand RNA synthesis from a full-length hepatitis C virus clone. J Med Virol. 2005;76:511–9. https://doi.org/10.1002/jmv.20391.
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Affiliations

Department of Pathology and Laboratory Medicine, Tulane University Health Sciences Center, 1430 Tulane Avenue, New Orleans, LA70112, USA
Ramesh Prabhu & Srikanta Dash
Department of Microbiology and Immunology, Tulane University Health Sciences Center, 1430 Tulane Avenue, New Orleans, LA, 70112, USA
Robert F. Garry

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Ramesh PrabhuView author publications
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Robert F. GarryView author publications
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Srikanta DashView author publications
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Corresponding author

Correspondence to Srikanta Dash.

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Prabhu, R., Garry, R.F. & Dash, S. Retraction Note: Small interfering RNA targeted to stem-loop II of the 5′ untranslated region effectively inhibits expression of six HCV genotypes. Virol J 18, 155 (2021). https://doi.org/10.1186/s12985-021-01623-y

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Published: 26 July 2021
DOI: https://doi.org/10.1186/s12985-021-01623-y

中文翻译：

撤稿说明：靶向 5' 非翻译区茎环 II 的小干扰 RNA 可有效抑制六种 HCV 基因型的表达

主编已撤回这篇文章。有人对一些数字提出了担忧，特别是：

图 4：pCVH77C/+siRNA74 面板似乎与 pCVJ4L6S/+siRNA74 面板重叠
图 4：pCVH77C/全长 HCV 面板似乎与 pM.O.9.6.-T7/+EBNA1 面板相同
图 6：底部中心和右下面板看起来是相同的

该文章还显示出与之前发表的文章 [1] 的显着重叠。因此，主编不再对文章中报告的某些数据的可靠性充满信心。

Robert F. Garry 和 Srikanta Dash 同意此撤销。编辑无法获得 Ramesh Prabhu 的当前电子邮件地址。

1.
Prabhu R、Vittal P、Yin Q、Flemington E、Garry R、Robichaux WH、Dash S. 小干扰 RNA 有效抑制全长丙型肝炎病毒克隆的蛋白质表达和负链 RNA 合成。医学杂志病毒学杂志。2005；76:511-9。https://doi.org/10.1002/jmv.20391。
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杜兰大学健康科学中心病理学和检验医学系，1430 Tulane Avenue, New Orleans, LA70112, USA
Ramesh Prabhu & Srikanta Dash
杜兰大学健康科学中心微生物学和免疫学系，1430 Tulane Avenue, New Orleans, LA, 70112, USA
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Prabhu, R., Garry, RF & Dash, S. Retraction 注：靶向 5' 非翻译区茎环 II 的小干扰 RNA 可有效抑制六种 HCV 基因型的表达。病毒学杂志 18, 155 (2021)。https://doi.org/10.1186/s12985-021-01623-y

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