The nucleus reticularis of the thalamus (nRT) is most studied in epilepsy for its role in the genesis of absence seizures; much less is known regarding its role in other seizure types, including those originating in limbic structures and the temporal lobe. As it is a major source of inhibitory input to higher order thalamic nuclei, stimulation of the nRT may be an effective strategy to disrupt seizure activity that requires thalamic engagement.

中文翻译：

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丘脑网状核的光遗传学激活通过抑制中线丘脑减轻边缘癫痫发作

丘脑网状核 (nRT) 在癫痫中研究最多的是其在失神发作发生中的作用；关于其在其他癫痫类型中的作用，包括源自边缘结构和颞叶的癫痫发作，人们知之甚少。由于它是高阶丘脑核团抑制输入的主要来源，因此刺激 nRT 可能是破坏需要丘脑参与的癫痫活动的有效策略。