Increasing evidence supports the significant role of short-range airborne transmission of viruses when in close contact with a source patient. A full-scale ventilated room (Cleanliness: ISO 14644–1 Class 5) and two face-to-face standing breathing thermal manikins were used to simulate a source individual and a susceptible person. Monodisperse particle generation and measurement techniques were used to evaluate the effect of virus-laden droplet nuclei size on short-range airborne transmission risk. We analysed four particle sizes (1.0, 1.5, 2.5, and 5.0 µm) to simulate the transport of exhaled droplet nuclei within an interpersonal distance of 0.5 m. The results indicated that the size distribution of airborne droplet nuclei could significantly influence transmission, with the inhalation fraction decreasing with increasing droplet nuclei size. Additionally, results showed that proximity to the source manikin could influence transmission. Inhalation fraction decreased with increasing interpersonal distance, fitting well with the 1/d rule of droplet nuclei concentration decay. Our findings improve the understanding of the mechanism of the disease transmission.

越来越多的证据支持病毒在与源患者密切接触时短距离空气传播的重要作用。一个全面通风的房间（清洁度：ISO 14644–1 5 级）和两个面对面站立的呼吸热假人被用来模拟源个体和易感个体。使用单分散粒子生成和测量技术来评估载有病毒的飞沫核大小对短程空气传播风险的影响。我们分析了四种粒径（1.0、1.5、2.5 和 5.0 µm）来模拟呼出的液滴核在 0.5 m 的人际距离内的传输。结果表明，空气中飞沫核的大小分布对传播有显着影响，吸入分数随着飞沫核大小的增加而降低。此外，结果表明靠近源人体模型可能会影响传播。吸入分数随着人际距离的增加而降低，与 1/d液滴核浓度衰减规则。我们的发现提高了对疾病传播机制的理解。