Although primary motor cortex (M1) transcranial direct current stimulation (tDCS) has an analgesic effect in fibromyalgia (FM), its neural mechanism remains elusive. We investigated whether M1-tDCS modulates a regional temporal variability of blood-oxygenation-level-dependent (BOLD) signals, an indicator of the brain's flexibility and efficiency and if this change is associated with pain improvement.

中文翻译：

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功能磁共振成像信号变异与纤维肌痛的神经调节相关

尽管初级运动皮层（M1）经颅直流电刺激（tDCS）对纤维肌痛（FM）具有镇痛作用，但其神经机制仍不清楚。我们研究了 M1-tDCS 是否调节血氧水平依赖性 (BOLD) 信号的区域时间变异性（大脑灵活性和效率的指标），以及这种变化是否与疼痛改善相关。