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Analytical model for managing hypotony after implantation surgery of a glaucoma drainage device
Biomechanics and Modeling in Mechanobiology ( IF 3.0 ) Pub Date : 2021-07-23 , DOI: 10.1007/s10237-021-01494-w
R Agujetas 1 , B Kudiesh 2, 3 , J I Fernández-Vigo 3, 4 , Julián García-Feijóo 3, 4 , J M Montanero 1
Affiliation  

The main aim of glaucoma treatment is to reduce the intraocular pressure (IOP). One of the most common surgical treatments of glaucoma is the implantation of a glaucoma drainage device to drain the aqueous humor from the anterior chamber to a filtration bleb, where the aqueous humor is absorbed. In some cases, the excess of drainage causes ocular hypotony, which constitutes a sight-threatening complication. To prevent hypotony after this intervention, surgeons frequently introduce a suture into the device tube, which increases the hydraulic resistance of the tube and, therefore, the IOP. This study aims to provide an analytical model to correct hypotony following implantation surgery of a glaucoma drainage device, which may help glaucoma surgeons decide on hypotony treatment. The results indicate that the IOP after implanting a cylindrical tube around 300 μm in diameter is essentially the same as that built up in the filtering bleb and can hardly be controlled by introducing a straight suture unless the suture diameter is slightly lower than that of the tube. On the contrary, when the tube diameter is smaller than, for example, 100 μm, significant reductions of the IOP can be obtained by introducing a thin suture into the tube.



中文翻译:


青光眼引流装置植入手术后处理低眼压的分析模型



青光眼治疗的主要目的是降低眼压(IOP)。青光眼最常见的手术治疗之一是植入青光眼引流装置,将房水从前房排出到滤过泡,房水在滤泡处被吸收。在某些情况下,引流过多会导致眼部张力过低,从而构成威胁视力的并发症。为了防止干预后出现眼压过低,外科医生经常将缝合线引入装置管中,这会增加管的液压阻力,从而增加眼压。本研究旨在提供一个分析模型来纠正青光眼引流装置植入手术后的低眼压,这可能有助于青光眼外科医生决定低眼压治疗。结果表明,植入直径约 300 μm 的圆柱形管后的眼压与过滤泡中形成的眼压基本相同,并且很难通过引入直缝线来控制,除非缝线直径略小于管的直径。相反,当管直径小于例如100μm时,可以通过将细缝线引入管中来获得IOP的显着降低。

更新日期:2021-07-23
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