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Analysis of the composition and antioxidant status of breast milk in women giving birth prematurely and on time.
PLOS ONE ( IF 2.9 ) Pub Date : 2021-07-23 , DOI: 10.1371/journal.pone.0255252
Agnieszka Chrustek 1 , Agnieszka Dombrowska-Pali 2 , Dorota Olszewska-Słonina 1
Affiliation  

BACKGROUND Breastfeeding with mother's milk is the best form of nutrition not only for newborn babies, but especially for premature babies, due to the health benefits of taking human food. OBJECTIVES The aim of the study was to examine the basic composition, cortisol concentration and antioxidant status of breast milk samples from women giving birth before 37 weeks of pregnancy and comparing it with milk samples from women giving birth after 37 weeks of pregnancy. METHODS The material for the study was milk taken from women giving birth before and after 37 weeks of pregnancy. The basic composition of breast milk was determined using a MIRIS analyzer, cortisol concentration in samples by an enzyme-linked immunosorbent test and their total antioxidant status was assessed by DPPH and FRAP methods. RESULTS It has been shown that the concentration of cortisol in samples of human milk in the group of women giving birth before 37 weeks was 13.95 ng / ml [4,71-86,84], while in the group of women giving birth after week 37 of pregnancy-10.31 ng / ml [2.35-39-02] (p = 0.014), while% inhibition of DPPH was 65.46% and 58.30%, respectively (p = 0.014). CONCLUSIONS Milk from women giving birth prematurely is qualitatively different from the milk of women giving birth on time. The total antioxidant status of preterm milk is higher than term milk, which promotes the development of premature babies. Higher cortisol levels in samples from women giving birth before 37 weeks of pregnancy may stimulate the digestive system.

中文翻译:

早产准时妇女母乳成分及抗氧化状态分析[J].

背景技术母乳喂养不仅对新生婴儿,而且特别是对早产儿来说都是最佳营养形式,因为食用人类食物对健康有益。目的 本研究的目的是检查怀孕 37 周前分娩的妇女的母乳样本的基本成分、皮质醇浓度和抗氧化状态,并将其与怀孕 37 周后分娩的妇女的母乳样本进行比较。方法 本研究的材料是从怀孕 37 周前后分娩的妇女中提取的乳汁。使用 MIRIS 分析仪测定母乳的基本成分,通过酶联免疫吸附试验测定样品中的皮质醇浓度,并通过 DPPH 和 FRAP 方法评估其总抗氧化状态。结果 37周前分娩组的母乳样本中皮质醇浓度为13.95 ng/ml [4,71-86,84] 37 的孕期-10.31 ng/ml [2.35-39-02] (p = 0.014),而 DPPH 的抑制百分比分别为 65.46% 和 58.30% (p = 0.014)。结论 早产妇女的乳汁与按时分娩的妇女的乳汁有质的不同。早产奶的总抗氧化状态高于足月奶,促进早产儿的发育。怀孕 37 周前分娩的女性样本中较高的皮质醇水平可能会刺激消化系统。而在妊娠 37 周后分娩的妇女组中,10.31 ng / ml [2.35-39-02] (p = 0.014),而 DPPH 的抑制百分比分别为 65.46% 和 58.30% (p = 0.014)。结论 早产妇女的乳汁与按时分娩的妇女的乳汁有质的不同。早产奶的总抗氧化状态高于足月奶,有利于早产儿的发育。怀孕 37 周前分娩的女性样本中较高的皮质醇水平可能会刺激消化系统。而在妊娠 37 周后分娩的妇女组中,10.31 ng / ml [2.35-39-02] (p = 0.014),而 DPPH 的抑制百分比分别为 65.46% 和 58.30% (p = 0.014)。结论 早产妇女的乳汁与按时分娩的妇女的乳汁有质的不同。早产奶的总抗氧化状态高于足月奶,促进早产儿的发育。怀孕 37 周前分娩的女性样本中较高的皮质醇水平可能会刺激消化系统。早产奶的总抗氧化状态高于足月奶,促进早产儿的发育。怀孕 37 周前分娩的女性样本中较高的皮质醇水平可能会刺激消化系统。早产奶的总抗氧化状态高于足月奶,促进早产儿的发育。怀孕 37 周前分娩的女性样本中较高的皮质醇水平可能会刺激消化系统。
更新日期:2021-07-23
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