The objectives of this study were to identify the associated factors with cancerous and precancerous lesions of cervix. In Africa, the incidence of uterine cervical neoplasms varies from one region to another, where most women with uterine cervical neoplasms are seen at an advanced stage. For this reason, uterine cervical neoplasms mass screening reduces the incidence and mortality due to this disease, similar to what is being done in Europe. A cross-sectional analytical study was conducted. Socio-demographic characteristics, gynaecological-obstetrical history, risk factors, data from visual inspection with acetic acid and visual inspection with Lugol, colposcopy impressions and results of cytological analysis were performed. A simple and multiple regression were performed to establish a statistically significant difference between certain factors and the presence of precancerous or cancerous lesions of uterine cervical. In this study, of 63 women diagnosed histologically, 43 had precancerous lesions and 20 had cancerous lesions. we found that being older than 35, having the first intercourse before 18, having an antecedent of STI, being a widow and using of tobacco were risk factors associated with precancerous lesions (p = 0.013 with OR = 3.44 (1.22-9.73), p = 0.009 with OR = 4.07 (1.69-13.08), p < 0.001 with OR = 3.80 (1.94-7.47), p < 0.001 with OR = 9.77 (3.87-24.70) and p < 0.001 with OR = 5.47 (2.60-11.52)) respectively. Only being older than 45, being a widow and using tobacco were risk factors associated with cancerous lesions (p = 0.021 with OR = 2.01 (1.58-3.56), p = 0.02 with OR = 2.96 (2.10-3.87), p = 0.041 with OR = 1.98 (1.46-2.44)) respectively. Among participants diagnosed with uterine cervical neoplasms, there was a significant association with the STI, marital status and smoking. Despite the integration of the detection of precancerous uterine cervical neoplasms lesions into health facilities in Gabon, uterine cervical neoplasms ranks second among women's cancers in terms of incidence and first in terms of mortality.

中文翻译：

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加蓬利伯维尔大学医院中心的子宫颈肿瘤大规模筛查：与癌前病变和癌变病变的相关因素。

本研究的目的是确定与宫颈癌和癌前病变相关的因素。在非洲，子宫颈肿瘤的发病率因地区而异，大多数患有子宫颈肿瘤的女性都处于晚期。出于这个原因，子宫颈肿瘤大规模筛查降低了这种疾病的发病率和死亡率，类似于欧洲正在做的事情。进行了横断面分析研究。进行了社会人口学特征、妇产科病史、危险因素、醋酸肉眼检查数据和 Lugol 肉眼检查数据、阴道镜印象和细胞学分析结果。进行了简单和多元回归以建立某些因素与子宫颈癌前病变或癌性病变的存在之间的统计学显着差异。在这项研究中，在 63 名经组织学诊断的女性中，43 名患有癌前病变，20 名患有癌性病变。我们发现 35 岁以上、18 岁前第一次性交、有 STI 前科、寡妇和吸烟是与癌前病变相关的危险因素（p = 0.013，OR = 3.44 (1.22-9.73)，p = 0.009，OR = 4.07 (1.69-13.08)，p < 0.001，OR = 3.80 (1.94-7.47)，p < 0.001，OR = 9.77 (3.87-24.70)，p < 0.001，OR = 1.20-1.56 ） 分别。只有 45 岁以上、寡妇和吸烟是与癌性病变相关的危险因素（p = 0.021，OR = 2。01 (1.58-3.56), p = 0.02, OR = 2.96 (2.10-3.87), p = 0.041, OR = 1.98 (1.46-2.44))。在被诊断患有子宫颈肿瘤的参与者中，性传播感染、婚姻状况和吸烟有显着关联。尽管在加蓬将癌前子宫颈肿瘤病变的检测整合到卫生设施中，但子宫颈肿瘤的发病率在女性癌症中排名第二，死亡率排名第一。