Background Subacute sclerosing panencephalitis is a progressive neurodegenerative disorder caused by a latent and mutant measles virus which is extremely rare in developed countries. The lack of effective treatments leads to the research of other anti-inflammatory and neuroprotective treatments. Case Here we present a case of a 17-year-old patient affected by subacute sclerosing panencephalitis who manifest a dramatic improvement in neurological and general clinical conditions, as well as an arrest in the progression of demyelinating process in the central nervous system, after the beginning of a high ratio ketogenic diet. Conclusions Given its anti-inflammatory, antioxidant and metabolic effects, we believe that ketogenic diet utilisation could be a rational approach, can be considered a safe add-on therapy, carrying on with only a minimal risk of adverse effects or interactions. The data that support the findings of this short report are available on request from the corresponding author (IDN).

中文翻译：

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生酮饮食治疗亚急性硬化性全脑炎一例临床及磁共振研究

背景 亚急性硬化性全脑炎是一种由潜伏和突变的麻疹病毒引起的进行性神经退行性疾病，在发达国家极为罕见。缺乏有效的治疗方法导致对其他抗炎和神经保护治疗的研究。案例 在这里，我们介绍了一个 17 岁的亚急性硬化性全脑炎患者的案例，他表现出神经系统和一般临床状况的显着改善，以及中枢神经系统脱髓鞘过程的进展，在开始高比例生酮饮食。结论 鉴于其抗炎、抗氧化和代谢作用，我们认为生酮饮食的利用可能是一种合理的方法，可以被认为是一种安全的附加疗法，仅以最小的不利影响或相互作用风险进行。支持本简短报告结果的数据可向通讯作者 (IDN) 索取。