Background

An interprofessional (IP) experience was created that demonstrated the roles and responsibilities of pharmacists and physicians in clinical implementation of pharmacogenomics (PGx). The IP experience focused on PGx-themed patient cases and application of genotyping results to drug therapy management.

Interprofessional education activity

In 2016 and 2017, third-year pharmacy students and first-year medical students were placed on interprofessional teams with two to three students each. The teams resolved PGx patient cases, medical students wrote prescriptions for altered drug therapy based on the PGx profiles of the patients, and pharmacy students assessed and provided feedback to medical students about the prescriptions. Student could also volunteer to be genotyped for CYP2C19*2, and the results were compared.

Discussion

The IP experience significantly enhanced PGx knowledge and increased the confidence of using PGx in patient cases for the majority of participants. The experience did not increase the recognition of each discipline's role in precision medicine in a statistically significant manner. Accurate prescription writing was challenging for the first-year medical students (44.3% prescriptions written correctly). The genotyping results did not deviate from a Hardy Weinberg equilibrium for this population.

Implications

IP experiences focused on PGx present an ideal opportunity to educate and initiate collaborations between pharmacists and physicians and to promote utilization of PGx in precision medicine. The roles and responsibilities for each discipline can be easily recreated in an IP experience to provide robust training to the students.

中文翻译：

---

促进药师在精准医学中的作用的跨专业教育经验

背景

创造了跨专业 (IP) 体验，展示了药剂师和医生在药物基因组学 (PGx) 临床实施中的作用和责任。IP 经验侧重于以 PGx 为主题的患者病例以及基因分型结果在药物治疗管理中的应用。

跨专业教育活动

2016 年和 2017 年，三年级药学学生和一年级医学生被安排在跨专业团队中，每个团队有 2 到 3 名学生。这些团队解决了 PGx 患者病例，医学生根据患者的 PGx 档案编写了改变药物治疗的处方，药学学生评估并向医学生提供了有关处方的反馈。学生也可以自愿接受 CYP2C19*2 基因分型，并对结果进行比较。

讨论

IP 体验显着增强了 PGx 知识，并增强了大多数参与者在患者病例中使用 PGx 的信心。这种经历并没有以统计学上显着的方式提高对每个学科在精准医学中的作用的认可。对于一年级医学生来说，准确的处方书写具有挑战性（44.3% 的处方书写正确）。基因分型结果并未偏离该群体的 Hardy Weinberg 平衡。

影响

专注于 PGx 的知识产权经验提供了一个理想的机会来教育和启动药剂师和医生之间的合作，并促进 PGx 在精准医学中的应用。每个学科的角色和职责可以在知识产权体验中轻松重新创建，为学生提供强有力的培训。