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Risk factors for the occurrence of peptic esophagitis following laparoscopic Heller-Dor surgery for esophageal achalasia
Diseases of the Esophagus ( IF 2.6 ) Pub Date : 2021-07-23 , DOI: 10.1093/dote/doab050
Kazuto Tsuboi 1, 2 , Fumiaki Yano 2 , Nobuo Omura 2, 3 , Masato Hoshino 2 , Se-Ryung Yamamoto 2 , Shunsuke Akimoto 2 , Takahiro Masuda 2 , Yuki Sakashita 2 , Naoko Fukushima 2 , Hideyuki Kashiwagi 1
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Summary Peptic esophagitis can occur as a complication of laparoscopic Heller-Dor surgery (LHD) among patients with esophageal achalasia. The goal of this study was to identify the characteristics of patients who have developed peptic esophagitis following LHD surgery along with the risk factors associated with the occurrence of peptic esophagitis. Among the 447 cases consisting of esophageal achalasia patients who underwent LHD as the primary surgery, we compared the patient background, pathophysiology, symptoms, and surgical outcomes according to whether or not peptic esophagitis occurred following surgery. We also attempted to use univariate and multivariate analyses to identify the risk factors for peptic esophagitis occurring following surgery. Esophagitis following surgery was confirmed in 67 cases (15.0%). With respect to the patient backgrounds for cases in which peptic esophagitis had occurred, a significantly higher number were male patients, with a significantly high occurrence of mucosal perforation during surgery in terms of surgical outcomes, along with a high occurrence of esophageal hiatal hernias in terms of postoperative course (P = 0.045, 0.041, and 0.022, respectively). However, there were no significant differences in terms of age, BMI, disease duration, preoperative symptoms, esophageal manometric findings, esophageal barium findings, and esophageal clearance. A multivariate analysis indicated independent risk factors for the occurrence of peptic esophagitis following LHD as being male, the occurrence of mucosal perforation during surgery, and the occurrence of esophageal hiatal hernias. Peptic esophagitis occurred following LHD in 15% of cases. Independent risk factors for the occurrence of peptic esophagitis following LHD included being male, the occurrence of mucosal perforation during surgery, and the occurrence of esophageal hiatal hernias following surgery.

中文翻译:

腹腔镜Heller-Dor食管贲门失弛缓症术后发生消化性食管炎的危险因素

总结 消化性食管炎可能是食管贲门失弛缓症患者腹腔镜 Heller-Dor 手术 (LHD) 的并发症。本研究的目的是确定 LHD 手术后发生消化性食管炎的患者的特征以及与发生消化性食管炎相关的危险因素。在接受 LHD 作为主要手术的 447 例食管贲门失弛缓症患者中,我们根据手术后是否发生消化性食管炎比较了患者背景、病理生理学、症状和手术结果。我们还尝试使用单变量和多变量分析来确定手术后发生消化性食管炎的危险因素。67 例(15.0%)确诊为术后食管炎。就发生消化性食管炎的病例的患者背景而言,男性患者的数量显着增加,就手术结果而言,手术期间黏膜穿孔的发生率显着较高,同时食管裂孔疝的发生率也较高。术后病程(分别为 P = 0.045、0.041 和 0.022)。然而,在年龄、BMI、病程、术前症状、食管测压结果、食管钡剂检查结果和食管清除率方面没有显着差异。多因素分析表明,LHD 后发生消化性食管炎的独立危险因素为男性、术中发生黏膜穿孔、发生食管裂孔疝。15% 的病例在 LHD 后发生消化性食管炎。LHD术后发生消化性食管炎的独立危险因素包括男性、术中发生黏膜穿孔、术后发生食管裂孔疝。
更新日期:2021-07-23
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