A new protocol was developed for the synthesis of azo pyrazole derivatives via one-pot reaction of β-ketonitriles and phenyl hydrazines in the presence of nano SiO₂ as a mild catalyst. The synthesized dyes were elucidated using spectrophotometry, mainly NMR; FTIR; UV as well as elemental analysis. The dyeing was carried out utilizing supercritical carbon dioxide as a green medium. Outstanding deep color shades and excellent dye fixation were exhibited by all new dyes. Furthermore, the dyed samples revealed superlative color fastness. The biological evaluation of both the dyestuffs and the dyed samples showed overgrowing antimicrobial activity against the tested microorganisms. Therefore, our findings assured that disperse reactive dyes are the most commercially appropriate materials for dyeing cotton in supercritical carbon dioxide.

开发了一种在纳米 SiO ₂存在下通过β-酮腈和苯肼的一锅反应合成偶氮吡唑衍生物的新方案作为温和的催化剂。合成的染料使用分光光度法（主要是核磁共振）进行阐明；红外光谱；紫外线和元素分析。使用超临界二氧化碳作为绿色介质进行染色。所有新染料都表现出出色的深色调和出色的染料固色能力。此外，染色样品显示出最高的色牢度。染料和染色样品的生物学评估显示对测试微生物的抗菌活性过度增长。因此，我们的研究结果保证了分散活性染料是在超临界二氧化碳中对棉进行染色的最适合商业化的材料。