Abstract

The synthesis of metal nanoparticles by a green method is eco-friendly, nontoxic and few benefits to the growing fields of research used inhibit bacteria and cancer growth over the recent years. In this study, CuO NPs are synthesized through Euphorbia hirta leaf extract. Formation of CuO NPs was confirmed by SPR peak at UV spectrum. FTIR identified functional groups are responsible for reduction and stabilization, GC–MS, phytochemicals present in the Euphorbia hirta extract accountable for synthesizing CuO NPs. XRD confirmed crystalline nature, SEM and TEM confirmed size and spherical morphology. Furthermore, CuO NPs effective antibacterial activity to inhibit pathogens, strong biological activities regarding antioxidant activity and anti-inflammatory activity and excellent anticancer activity against the Ht-29 cell line. Also, good catalyst for the effective degradation of methylene blue. The present study suggests that biosynthesized CuO NPs through an extract from Euphorbia hirta may be used for therapeutic application in future clinical studies.

摘要

通过绿色方法合成金属纳米颗粒是环保的、无毒的，并且对近年来用于抑制细菌和癌症生长的研究领域的发展几乎没有什么好处。在本研究中，CuO NPs 是通过大戟叶提取物合成的。通过紫外光谱的 SPR 峰证实了 CuO NPs 的形成。FTIR 鉴定的官能团负责还原和稳定化、GC-MS、大戟中存在的植物化学物质提取负责合成CuO NPs。XRD 证实了结晶性质，SEM 和 TEM 证实了尺寸和球形形态。此外，CuO NPs 具有抑制病原体的有效抗菌活性、抗氧化活性和抗炎活性的强大生物活性以及对 Ht-29 细胞系的优异抗癌活性。也是有效降解亚甲蓝的良好催化剂。本研究表明，通过大戟提取物生物合成的 CuO NPs可用于未来临床研究的治疗应用。