Gender minority stress refers to social stressors such as discrimination and stigma that gender minorities are subject to. This study examines the relationship between gender minority stress and psychological well-being in trans and gender diverse young people (TGDYP). We used a cross-sectional design to investigate the relationship between gender minority stress and mental well-being in TGDYP aged 16–25. We measured anxiety, depression, general psychological well-being, gender dysphoria, gender minority stress (distal and proximal), resilience and heteronormative beliefs in cisgender (n = 135) and trans and gender diverse (TGD) (n = 106) participants. Hierarchical regression was used to analyse the data. TGD participants had significantly higher levels of anxiety and depression, and poorer general well-being, than cisgender participants. Although the direction of the relationship cannot be determined through our analysis, TGD participants who experienced more minority stress and were assigned female at birth had higher levels of depression and anxiety. TGD participants with higher resilience scores and were assigned male at birth had better well-being overall. Our findings suggest that we should pay attention to minority stress when thinking about how to reduce anxiety and depression in TGDYP. The responsibility for improving well-being lies not just with services but instead should be held by our whole society.

性别少数压力是指社会压力源，例如性别少数群体受到的歧视和污名化。本研究调查了跨性别和性别多样化的年轻人 (TGDYP) 的性别少数压力与心理健康之间的关系。我们使用横断面设计来调查 16-25 岁的 TGDYP 中性别少数派压力与心理健康之间的关系。我们测量了顺性别 ( n = 135) 和跨性别和性别多样化 (TGD) ( n= 106) 参与者。使用分层回归来分析数据。与顺性别参与者相比，TGD 参与者的焦虑和抑郁水平明显更高，总体幸福感更差。虽然我们的分析无法确定这种关系的方向，但经历更多少数族裔压力并在出生时被分配为女性的 TGD 参与者的抑郁和焦虑程度更高。恢复力得分较高且出生时被分配为男性的 TGD 参与者总体幸福感更好。我们的研究结果表明，在考虑如何减轻 TGDYP 中的焦虑和抑郁时，我们应该注意少数派压力。改善福祉的责任不仅在于服务，而应由我们全社会共同承担。