Organisms have cellular machinery that is focused on optimum utilization of resources to maximize growth and survival depending on various environmental and developmental factors. Catabolite repression is a strategy utilized by various species of bacteria and fungi to accommodate changes in the environment such as the depletion of resources, or an abundance of less-favored nutrient sources. Catabolite repression allows for the rapid use of certain substrates like glucose over other carbon sources. Effective handling of carbon and nitrogen catabolite repression in microorganisms is crucial to outcompete others in nutrient limiting conditions. Investigations into genes and proteins linked to preferential uptake of different nutrients under various environmental conditions can aid in identifying regulatory mechanisms that are crucial for optimum growth and survival of microorganisms. The exact time and way bacteria and fungi switch their utilization of certain nutrients is of great interest for scientific, industrial, and clinical reasons. Catabolite repression is of great significance for industrial applications that rely on microorganisms for the generation of valuable bio-products. The impact catabolite repression has on virulence of pathogenic bacteria and fungi and disease progression in hosts makes it important area of interest in medical research for the prevention of diseases and developing new treatment strategies. Regulatory networks under catabolite repression exemplify the flexibility and the tremendous diversity that is found in microorganisms and provides an impetus for newer insights into these networks.

生物体具有细胞机制，专注于资源的最佳利用，以根据各种环境和发育因素最大限度地增长和生存。分解代谢物抑制是各种细菌和真菌用来适应环境变化的策略，例如资源枯竭或不利的营养来源丰富。分解代谢物抑制允许快速使用某些底物，例如葡萄糖而不是其他碳源。有效处理微生物中的碳和氮分解代谢物抑制对于在营养限制条件下击败其他人至关重要。研究与在各种环境条件下优先吸收不同营养物质相关的基因和蛋白质，有助于确定对微生物的最佳生长和存活至关重要的调控机制。出于科学、工业和临床原因，细菌和真菌转换对某些营养物质的利用的确切时间和方式具有重要意义。分解代谢物抑制对于依赖微生物产生有价值的生物产品的工业应用具有重要意义。分解代谢物抑制对病原细菌和真菌的毒力以及宿主的疾病进展的影响使其成为预防疾病和开发新治疗策略的医学研究的重要领域。