Salinity and wastewater pollution in mangrove ecosystems can affect microorganisms and the abundance of genes involved in response to these stressors. This research aimed to identify genes associated with resistance and biosynthesis of antimicrobial compounds in mangrove soils subjected to contrasting salinities and wastewater pollution. Samples of rhizospheric soil were taken from a mangrove at the mouth of the Ranchería River in La Guajira, Colombia. A functional analysis was performed using Illumina HiSeq 2500 sequencing data obtained from total DNA extracted. Increased salt concentration influenced metabolic pathways and differential abundance of genes associated with the synthesis of antimicrobial compounds (e.g., rfbB/rffG, INO1/ISYNA1, rfbA/rffH, sat/met3, asd). Also, among 33 genes involved in intrinsic antibiotic resistance, 16 were significantly influenced by salinity (e.g., cusR/copR/silR, vgb, tolC). We concluded that salt stress tolerance and adaptive mechanisms could favor the biosynthesis of antimicrobial compounds in mangroves contaminated by sewage.

红树林生态系统中的盐度和废水污染会影响微生物和参与应对这些压力的基因的丰度。这项研究旨在确定与受到对比盐度和废水污染的红树林土壤中抗​​微生物化合物的抗性和生物合成相关的基因。根际土壤样本取自哥伦比亚拉瓜希拉 Ranchería 河口的红树林。使用从提取的总 DNA 中获得的 Illumina HiSeq 2500 测序数据进行功能分析。盐浓度的增加影响了与抗菌化合物合成相关的基因的代谢途径和差异丰度（例如，rfbB/rffG、INO1/ISYNA1、rfbA/rffH、sat/met3 , asd )。此外，除涉及固有抗生素抗性基因33，16分别通过显著盐度影响（例如，cusR / COPR / silR，VGB，TOLC）。我们得出结论，盐胁迫耐受性和适应性机制可能有利于被污水污染的红树林中抗菌化合物的生物合成。