Objective The aim of this study was to determine the prevalence and taxonomy of pathogen codetection in pediatric case fatalities associated with adenoviral respiratory infection.

Methods This retrospective case series included 107 pediatric case fatalities associated with adenoviral respiratory infection.

Results We observed a high rate of pathogen codetection with broad diversity from both respiratory and nonrespiratory sources. We noted differences in codetection characteristics based on immune status; most notably that immunocompromised cases were more likely to have bacteremia and adenoviremia.

Conclusions In pediatric case fatalities associated with adenoviral respiratory infection, we observed a high degree of pathogen codetection.

目的 本研究的目的是确定病原体联合检测在与腺病毒呼吸道感染相关的儿科病例死亡中的流行率和分类学。

方法 该回顾性病例系列包括 107 例与腺病毒呼吸道感染相关的儿科死亡病例。

结果 我们观察到来自呼吸道和非呼吸道来源的病原体联合检测率很高，具有广泛的多样性。我们注意到基于免疫状态的编码检测特征的差异；最值得注意的是，免疫功能低下的病例更有可能出现菌血症和腺病毒血症。

结论 在与腺病毒呼吸道感染相关的儿科死亡病例中，我们观察到高度的病原体共检测。