Aurora A is a serine/threonine kinase essential for mitotic entry and spindle assembly. Recent molecular studies have revealed the existence of multiple, distinct mechanisms of Aurora A activation, each occurring at specific subcellular locations, optimized for cellular context, and primed by signaling events including phosphorylation and oxidation.

中文翻译：

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Aurora A 激酶激活：不同手段达到不同目的


Aurora A 是一种丝氨酸/苏氨酸激酶，对于有丝分裂进入和纺锤体组装至关重要。最近的分子研究揭示了 Aurora A 激活存在多种不同的机制，每种机制都发生在特定的亚细胞位置，针对细胞环境进行了优化，并由磷酸化和氧化等信号事件引发。