Introduction: Mild cognitive impairment (MCI) represents a target for early detection and intervention in dementia, yet there is a shortage of validated screening tools in Arabic to diagnose MCI. The mini-Addenbrooke’s Cognitive Examination (m-ACE) is a brief cognitive battery that is scored out of 30 and can be administered in under 5 min providing a quick screening tool for assessment of cognition. Objective: We aimed to validate the m-ACE in Arabic speakers in Egypt with MCI to provide cut-off scores. Methods: We included 24 patients with MCI and 52 controls and administered the Arabic version of the m-ACE. Results: There was a statistically significant difference (p #x3c; 0.0001) on the total m-ACE score between MCI patients (mean 18.54, SD 3.05) and controls (mean 24.54, SD 2.68). There was also a statistically significant difference between MCI patients and controls on the total score and the fluency, visuospatial, and memory recall sub-scores of the m-ACE (p #x3c; 0.05). Performance on the m-ACE significantly correlated with both the Mini-Mental State Examination (MMSE) and the Addenbrooke’s Cognitive Examination-III (ACE-III). Using a receiver operator characteristic curve, the optimal cut-off score for MCI on the m-ACE total score was 21 out of 30 (87.5% sensitivity, 84.6% specificity, and 85.5% accuracy). Conclusions: We validated the Arabic m-ACE in Egyptian patients with MCI and provided objective validation of it as a screening tool for MCI, with good sensitivity, specificity, and accuracy that is comparable to other translated versions of the m-ACE in MCI.
Dement Geriatr Cogn Disord

中文翻译：

---

Mini-Addenbrooke 认知检查在阿拉伯语人士轻度认知障碍中的验证

简介：轻度认知障碍 (MCI) 是早期发现和干预痴呆症的目标，但缺乏经过验证的阿拉伯语筛查工具来诊断 MCI。迷你阿登布鲁克认知检查 (m-ACE) 是一种简短的认知测试，总分为 30 分，可在 5 分钟内完成，为评估认知提供了一种快速筛选工具。目标：我们旨在通过 MCI 验证埃及阿拉伯语使用者的 m-ACE，以提供截止分数。方法：我们纳入了 24 名 MCI 患者和 52 名对照组，并给予了阿拉伯版本的 m-ACE。结果：有统计学显着差异（ p#x3c; MCI 患者（平均 18.54，SD 3.05）和对照组（平均 24.54，SD 2.68）之间的总 m-ACE 评分为 0.0001）。MCI 患者和对照组之间在 m-ACE 的总分和流畅性、视觉空间和记忆回忆子分数上也存在统计学上的显着差异 ( p #x3c; 0.05)。m-ACE 的表现与简易精神状态检查 (MMSE) 和阿登布鲁克认知检查-III (ACE-III) 显着相关。使用接受者操作特征曲线，m-ACE 总分中 MCI 的最佳截止分数为 21 分，共 30 分（敏感性 87.5%，特异性 84.6%，准确度 85.5%）。结论：我们在埃及 MCI 患者中验证了阿拉伯语 m-ACE，并对其作为 MCI 筛查工具进行了客观验证，具有与 MCI 中 m-ACE 的其他翻译版本相媲美的良好灵敏度、特异性和准确性。
老年痴呆症认知障碍