Type O blood group associates with higher anti-JC polyomavirus antibody levels,Brain and Behavior

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Type O blood group associates with higher anti-JC polyomavirus antibody levels
Brain and Behavior ( IF 2.6 ) Pub Date : 2021-07-21 , DOI: 10.1002/brb3.2298
Pia Frenken ₁ , Hans-Peter Hartung ₂ , Tomas Olsson ₃ , Ortwin Adams ₁ , Clemens Warnke _{2,

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Affiliation

Patients with multiple sclerosis (MS) and high anti-JC polyomavirus (JCPyV) antibodies in blood have an increased risk for the development of progressive multifocal leukoencephalopathy (PML) when treated for MS. To test the hypothesis that type O blood group associates with anti-JCPyV antibody levels and the risk of developing PML, we characterized ABO blood group antigen on blood samples of 62 patients with PML, and 64 MS controls without PML.

中文翻译：

O 型血型与较高的抗 JC 多瘤病毒抗体水平相关

多发性硬化症 (MS) 和血液中高抗 JC 多瘤病毒 (JCPyV) 抗体的患者在接受 MS 治疗时发生进行性多灶性白质脑病 (PML) 的风险增加。为了检验 O 型血型与抗 JCPyV 抗体水平和发生 PML 风险相关的假设，我们对 62 名 PML 患者和 64 名无 PML 的 MS 对照的血液样本中的 ABO 血型抗原进行了表征。

更新日期：2021-09-03

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