Molecular evidence suggesting the persistence of residual SARS-CoV-2 and immune responses in the placentas of pregnant patients recovered from COVID-19,Cell Proliferation

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Molecular evidence suggesting the persistence of residual SARS-CoV-2 and immune responses in the placentas of pregnant patients recovered from COVID-19
Cell Proliferation ( IF 5.9 ) Pub Date : 2021-07-22 , DOI: 10.1111/cpr.13091
Hao Wu _{1,

2,

3,

4} , Shujie Liao ₅ , Yiming Wang _{1,

2,

3,

4} , Ming Guo ₆ , Xingguang Lin ₅ , Jianli Wu ₅ , Renjie Wang ₅ , Dan Lv ₅ , Di Wu ₅ , Mengzhou He ₅ , Bai Hu ₅ , Rui Long ₅ , Jing Peng ₇ , Hui Yang ₇ , Heng Yin ₇ , Xin Wang ₆ , Zhixiang Huang ₆ , Ke Lan ₆ , Yanbin Zhou ₈ , Wei Zhang ₉ , Zhenyu Xiao _{1,

2,

4} , Yun Zhao ₇ , Dongrui Deng ₅ , Hongmei Wang _{1,

2,

3,

4}

Affiliation

Recent studies have shown the presence of SARS-CoV-2 in the tissues of clinically recovered patients and persistent immune symptoms in discharged patients for up to several months. Pregnant patients were shown to be a high-risk group for COVID-19. Based on these findings, we assessed SARS-CoV-2 nucleic acid and protein retention in the placentas of pregnant women who had fully recovered from COVID-19 and cytokine fluctuations in maternal and foetal tissues.

中文翻译：

分子证据表明，从 COVID-19 恢复的孕妇的胎盘中持续存在残留 SARS-CoV-2 和免疫反应

最近的研究表明，临床康复患者的组织中存在 SARS-CoV-2，出院患者的免疫症状持续长达数月。怀孕患者被证明是感染 COVID-19 的高危人群。基于这些发现，我们评估了从 COVID-19 中完全康复的孕妇胎盘中的 SARS-CoV-2 核酸和蛋白质滞留情况以及母体和胎儿组织中的细胞因子波动。

更新日期：2021-09-20

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