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Single-neuron correlate of epilepsy-related cognitive deficits in visual recognition memory in right mesial temporal lobe
Epilepsia ( IF 6.6 ) Pub Date : 2021-07-21 , DOI: 10.1111/epi.17010
Seung J Lee 1, 2 , Danielle E Beam 1 , Andrea G P Schjetnan 3 , Lynn K Paul 4 , Nand Chandravadia 1 , Chrystal M Reed 5 , Jeffrey M Chung 5 , Ian B Ross 6 , Taufik A Valiante 3, 7 , Adam N Mamelak 1 , Ueli Rutishauser 1, 5, 8, 9
Affiliation  

Impaired memory is a common comorbidity of refractory temporal lobe epilepsy (TLE) and often perceived by patients as more problematic than the seizures themselves. The objective of this study is to understand what the relationship of these behavioral impairments is to the underlying pathophysiology, as there are currently no treatments for these deficits, and it remains unknown what circuits are affected.

中文翻译:

右侧颞叶内侧视觉识别记忆中癫痫相关认知缺陷的单神经元相关性

记忆障碍是难治性颞叶癫痫 (TLE) 的常见合并症,患者通常认为比癫痫发作本身更成问题。本研究的目的是了解这些行为障碍与潜在的病理生理学之间的关系,因为目前还没有针对这些缺陷的治疗方法,并且仍然不清楚哪些电路受到影响。
更新日期:2021-08-29
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