Objective: The present study is one of the few population-based studies that have been conducted in the Middle East, aimed to determine the incidence of stroke in Qom, one of the central provinces of Iran.

Methods: The Qom province includes an estimated at-risk population of about 1 million. During a twelve-month period (November 2018–November 2019), all first-ever strokes occurring in the target population were registered. Hospitalized cases were ascertained by discharge codes. Out-of-hospital cases were ascertained by a prospective screening of EMS services, emergency departments, ambulances records, primary care clinics, rural and urban public health centers, primary care physician offices, and neurologists' offices. Crude and age-adjusted incidence rates (per 100,000 person-years) were calculated using the direct method with the world standard population.

Results: During the study period, 1462 first-ever strokes occurred with a mean age of 68.1 (17-103) years, of these, 45.2% were female (661 cases). The crude annual incidence rate per 100,000 at-risk populations was 145.4 (95% CI, 138.1 to 153.0) for all types of stroke (156.5 for male and 134.3 for female), 26.4 (95% CI, 23.5 to 29.8) for hemorrhagic stroke, and 114 (95% CI, 105 to 121) for ischemic stroke. The incidence rate adjusted to the world population was 201.4 (95% CI, 193-210) per 100,000 at-risk populations (adj incidence, 218.5 for male vs 187.4 for female). The total fatality rate during the first 28 days, was 19.6%.

Conclusion: This study confirms the higher incidence of stroke and at a younger age, in this region, accompanied by the higher prevalence of underlying stroke risk factors than the global average.

目标：本研究是在中东进行的为数不多的基于人群的研究之一，旨在确定伊朗中部省份之一库姆的中风发病率。

方法：库姆省估计有大约 100 万高危人群。在十二个月期间（2018 年 11 月至 2019 年 11 月），登记了目标人群中发生的所有首次中风。住院病例按出院代码确定。通过对 EMS 服务、急诊室、救护车记录、初级保健诊所、农村和城市公共卫生中心、初级保健医生办公室和神经科医生办公室进行前瞻性筛查来确定院外病例。使用世界标准人口的直接方法计算粗发病率和年龄调整后的发病率（每 100,000 人年）。

结果：在研究期间，1462 例首次中风发生，平均年龄为 68.1（17-103）岁，其中 45.2% 为女性（661 例）。对于所有类型的中风（男性为 156.5，女性为 134.3），每 100,000 名高危人群的粗年发病率为 145.4（95% CI，138.1 至 153.0），出血性中风为 26.4（95% CI，23.5 至 29.8） , 和 114 (95% CI, 105 to 121) 对于缺血性卒中。根据世界人口调整后的发病率为每 100,000 名高危人群 201.4（95% CI，193-210）（调整发病率，男性为 218.5，女性为 187.4）。前 28 天的总死亡率为 19.6%。

结论：本研究证实，该地区卒中发病率较高且年龄较小，同时潜在卒中危险因素的患病率高于全球平均水平。