In this work we study the transmission of Trypanosoma brucei gambiense (Tbg), which causes the Human African Trypanosomiasis, also known as sleeping sickness disease, very common in African rural areas. Simulations were implemented using agent-based modeling approach, where agents were split into three groups: humans, animals and flies. Humans and animals are the reservoirs for the trypanosoma and the interaction between them (transmission of the pathogen), depends exclusively on the third group, the disease vector, the tsetse fly. We applied a type of treatment based on the drug Fexinidazole in different percentages for the human population, aiming the optimization of treatment resources to minimize costs and maximize the efficacy of this new drug in rural zones of the Democratic Republic of the Congo (DRC). Simulations of different scenarios show that the disease eradication is possible depending on the available resources (medication, health team) to be used.

在这项工作中，我们研究了冈比亚布氏锥虫（Tbg)，它导致人类非洲锥虫病，也称为昏睡病，在非洲农村地区非常常见。模拟是使用基于代理的建模方法实现的，其中代理分为三组：人类、动物和苍蝇。人和动物是锥虫的宿主，它们之间的相互作用（病原体的传播）完全取决于第三类，即疾病媒介，采采蝇。我们对人群应用了一种基于药物非昔硝唑的不同百分比的治疗，旨在优化治疗资源，以最大限度地降低成本并最大限度地提高这种新药在刚果民主共和国 (DRC) 农村地区的疗效。