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A two-stage amplified PZT sensor for monitoring lung and heart sounds in discharged pneumonia patients
Microsystems & Nanoengineering ( IF 7.3 ) Pub Date : 2021-07-22 , DOI: 10.1038/s41378-021-00274-x
Hongbin Chen 1 , Shuai Yu 2 , Haiyang Liu 3 , Jie Liu 3 , Yongguang Xiao 4 , Dandan Wu 1 , Xiaoyu Pan 5 , Cuihong Zhou 5 , Yifeng Lei 3 , Sheng Liu 3, 6
Affiliation  

Assessment of lung and heart states is of critical importance for patients with pneumonia. In this study, we present a small-sized and ultrasensitive accelerometer for continuous monitoring of lung and heart sounds to evaluate the lung and heart states of patients. Based on two-stage amplification, which consists of an asymmetric gapped cantilever and a charge amplifier, our accelerometer exhibited an extremely high ratio of sensitivity to noise compared with conventional structures. Our sensor achieves a high sensitivity of 9.2 V/g at frequencies less than 1000 Hz, making it suitable to use to monitor weak physiological signals, including heart and lung sounds. For the first time, lung injury, heart injury, and both lung and heart injuries in discharged pneumonia patients were revealed by our sensor device. Our sound sensor also successfully tracked the recovery course of the discharged pneumonia patients. Over time, the lung and heart states of the patients gradually improved after discharge. Our observations were in good agreement with clinical reports. Compared with conventional medical instruments, our sensor device provides rapid and highly sensitive detection of lung and heart sounds, which greatly helps in the evaluation of lung and heart states of pneumonia patients. This sensor provides a cost-effective alternative approach to the diagnosis and prognosis of pneumonia and has the potential for clinical and home-use health monitoring.



中文翻译:


用于监测出院肺炎患者肺音和心音的两级放大 PZT 传感器



肺和心脏状态的评估对于肺炎患者至关重要。在这项研究中,我们提出了一种小型超灵敏加速度计,用于连续监测肺音和心音,以评估患者的肺和心脏状态。基于由不对称间隙悬臂梁和电荷放大器组成的两级放大,我们的加速度计与传统结构相比表现出极高的灵敏度与噪声比。我们的传感器在低于 1000 Hz 的频率下实现了 9.2 V/g 的高灵敏度,使其适合用于监测微弱的生理信号,包括心音和肺音。我们的传感器设备首次显示了出院肺炎患者的肺损伤、心脏损伤以及肺和心脏损伤。我们的声音传感器还成功追踪了出院肺炎患者的康复过程。随着时间的推移,出院后患者的肺部和心脏状况逐渐好转。我们的观察结果与临床报告非常一致。与传统医疗仪器相比,我们的传感器设备可以快速、高灵敏度地检测肺音和心音,这对于评估肺炎患者的肺音和心脏状态有很大帮助。该传感器为肺炎的诊断和预后提供了一种经济高效的替代方法,并具有临床和家庭使用健康监测的潜力。

更新日期:2021-07-22
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