Triazole resistant Aspergillus fumigatus in an Israeli patient with Chronic Cavitary Pulmonary Aspergillosis due to a novel E306K Substitution in Hmg1,Antimicrobial Agents and Chemotherapy

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Triazole resistant Aspergillus fumigatus in an Israeli patient with Chronic Cavitary Pulmonary Aspergillosis due to a novel E306K Substitution in Hmg1
Antimicrobial Agents and Chemotherapy ( IF 4.1 ) Pub Date : 2021-07-19 , DOI: 10.1128/aac.01089-21
Mariana Handelman ₁ , Alma Morogovsky ₁ , Wei Liu ₂ , Ronen Ben-Ami ₃ , Nir Osherov ₁

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Triazole resistance in the pathogenic mold Aspergillus fumigatus has increased worldwide, posing a growing therapeutic challenge. Recently, mutations in the 3-hydroxy-3-methyl-glutaryl-coenzyme A (HMG-CoA) reductase gene (hmg1) have been associated with ...

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