Paper spray ionization mass spectrometry (PS-MS) is employed herein as a convenient platform to investigate an on-surface catalytic process, that is, the oxidation of alcohols induced by ruthenium salts. The tag-charged benzyl alcohol 1 (m/z 166), used as a suitable prototype starting substrate, is quickly oxidized by tert-butyl hydroperoxide (TBHP) in an on-surface process catalyzed by ruthenium trichloride (RuCl3). The PS(+)-MS revealed the formation of products from the oxidation of alcohol 1. RuCl3 and TBHP played a crucial role in this process since when salts of other metals (platinum, palladium, and iron) and another oxidizing agent (hydrogen peroxide) are employed, no reaction is observed. Moreover, UV radiation and heating accelerate the on-surface alcohol 1 oxidation. Finally, an exciting possibility is to employ PS-MS to investigate similar organic catalytic reactions to accelerate them and detect unstable intermediates, indiscernible in the condensed phase.

中文翻译：

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通过纸喷雾质谱法监测的表面醇氧化：钌作为催化剂的作用。

本文采用纸喷雾电离质谱 (PS-MS) 作为研究表面催化过程的便捷平台，即由钌盐诱导的醇的氧化。带标签的苯甲醇 1 (m/z 166)，用作合适的原型起始底物，在三氯化钌 (RuCl3) 催化的表面过程中被叔丁基过氧化氢 (TBHP) 快速氧化。PS(+)-MS 揭示了酒精 1 氧化产物的形成。RuCl3 和 TBHP 在此过程中起着至关重要的作用，因为当其他金属（铂、钯和铁）的盐和另一种氧化剂（过氧化氢） ) 被使用，没有观察到反应。此外，紫外线辐射和加热会加速表面醇 1 的氧化。最后，