Two new pregnane glycosides were isolated from the leaves of Gymnema sylvestre (Retz.) R.Br. ex Sm. Their chemical structures were determined as (20S)−12β-tigloyloxy-5α-hydroperoxy-3β,8β,14β,17β,20-pentahydroxypregn-6-ene 3-O-β-D-glucopyranosyl-(1→4)‐6-deoxy-3-O-methyl-β-D-allopyranosyl-(1→4)-β-D-oleandropyranosyl-(1→4)-β-D-cymaropyranosyl-(1→4)-β-D-cymaropyranoside (1) and (20S)−12β-benzoyloxy-5α-hydroperoxy-3β,8β,14β,17β,20-pentahydroxypregn-6-ene 3-O-β-D-glucopyranosyl-(1→4)‐6-deoxy-3-O-methyl-β-D-allopyranosyl-(1→4)-β-D-oleandropyranosyl-(1→4)-β-D-cymaropyranosyl-(1→4)-β-D-cymaropyranoside (2) on the basis of the extensive spectroscopic methods, including 1D, 2D NMR, HRESIMS, and in comparison with the reported data. At the concentration of 200 µM, compounds 1 and 2 showed moderate anti α-glucosidase and α-amylase activities with inhibitory percentage of 31.1 ± 1.2 and 42.3 ± 1.7% (for α-glucosidase), and 27.8 ± 1.3 and 34.5 ± 1.5% (for α-amylase), respectively.

从匙羹藤( Gymnema sylvestre (Retz.) R.Br.)的叶子中分离出两种新的孕烷苷。前 Sm。它们的化学结构确定为 (20 S )−12 β -tigloyloxy-5 α -hydroperoxy- 3 β ,8 β ,14 β ,17 β ,20-pentahydroxypregn-6-ene 3 -O-β -D-glucopyranosyl- （1→4）-6-脱氧-3- ö甲基β -D- allopyranosyl-（1→4） - β -D- oleandropyranosyl-（1→4） - β -D- cymaropyranosyl-（1→4 )- β -D-cymaropyranoside ( 1 ) 和 (20 S )-12 β -benzoyloxy -5α -hydroperoxy-3 β，8 β，14 β，17 β，20-pentahydroxypregn -6-烯-3- O-β -D-吡喃葡萄糖基- （1→4）-6-脱氧-3- ö甲基β -D-allopyranosyl-（1→4） - β -D- oleandropyranosyl-（1→4） - β -D- cymaropyranosyl-（1→4） - β -D- cymaropyranoside（2）广泛的光谱的基础上方法，包括 1D、2D NMR、HRESIMS，并与报告的数据进行比较。在 200 µM 浓度下，化合物1和2显示出中度的抗α-葡萄糖苷酶和α-葡萄糖苷酶-淀粉酶活性的抑制百分比分别为 31.1 ± 1.2 和 42.3 ± 1.7%（对于α -葡萄糖苷酶），以及 27.8 ± 1.3 和 34.5 ± 1.5%（对于α -淀粉酶）。