Protective effects of alpha-lipoic acid on hair cell damage in diabetic zebrafish model,Molecular Genetics and Metabolism Reports

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Protective effects of alpha-lipoic acid on hair cell damage in diabetic zebrafish model
Molecular Genetics and Metabolism Reports ( IF 1.9 ) Pub Date : 2021-07-21 , DOI: 10.1016/j.ymgmr.2021.100783
Eunmi Kim ₁ , Dong-Won Lee ₁ , Hae-Chul Park ₁ , Dong Hwee Kim ₂

Affiliation

Hearing impairment is one of the complications in diabetes mellitus; however, there are very few therapeutic studies on it. In this study, we investigated the protective effect of alpha-lipoic acid (ALA) on hearing loss in diabetic transgenic zebrafish and confirmed that ALA protects the loss of hair cells (HCs) caused by hyperglycemia. The data indicated that ALA has a protective effect on the damage to HCs in diabetic zebrafish.

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