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miR-193a-3p Enhanced the Chemosensitivity to Trametinib in Gallbladder Carcinoma by Targeting KRAS and Downregulating ERK Signaling
Cancer Biotherapy and Radiopharmaceuticals ( IF 2.4 ) Pub Date : 2021-07-20 , DOI: 10.1089/cbr.2021.0016
Ganghua Yang 1 , Qinhong Xu 1 , Yong Wan 1 , Lei Zhang 1 , Zheng Wang 2 , Fandi Meng 1
Affiliation  

Objective: In this study, the authors identified miR-193a-3p as a tumor-suppressing microRNA, and its effects on the chemosensitivity to trametinib in gallbladder carcinoma (GBC) were evaluated.

中文翻译:

miR-193a-3p 通过靶向 KRAS 和下调 ERK 信号增强胆囊癌对 Trametinib 的化疗敏感性

目的:在本研究中,作者将 miR-193a-3p 鉴定为一种抑癌 microRNA,并评估了其对胆囊癌 (GBC) 曲美替尼化疗敏感性的影响。
更新日期:2021-07-21
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