Objective. Diabetic peripheral neuropathy (DPN) is one of the most common chronic complications of diabetes, leading to disability and decreased quality of life. In past research and clinical studies, the lower limb function of DPN patients was often the principal subject of research, with little attention given to the upper limb and hand. Our goal was to assess and compare hand function between elderly diabetic patients with DPN and without DPN. Methods. A total of 52 diabetic patients were registered and underwent hand function assessments and electrodiagnostic tests. Dynamometer, pinch meter, Semmes Weinstein monofilaments, and the Purdue Pegboard Test (PPT) were used to assess the patients’ grip strength, pinch strength, tactile sensory threshold, and hand dexterity. Results. Compared with the non-DPN group, the elderly DPN group showed worse thumb-middle fingertip pinch strength and thumb-little fingertip pinch strength in the dominant hand (3.50 (2.50, 4.25) vs. 4.50 (3.00, 5.00), ; 1.50 (1.00, 2.00) vs. 2.50 (2.00, 3.00), ); the elderly DPN group displayed worse thumb-middle fingertip pinch strength, thumb-ring fingertip pinch strength, and thumb-little fingertip pinch strength in the nondominant hand (3.50 (2.00, 4.50) vs. 4.00 (3.00, 5.00), ; 2.50 (1.25, 3.00) vs. 3.00 (2.50, 3.50), ; 1.00 (0.75, 2.25) vs. 2.50 (2.00, 2.50), ). The elderly DPN group scored lower than the non-DPN group on the PPT test of assembly ( vs. , , ). Conclusion. Motor function limitation is the principal hand dysfunction in elderly patients with DPN, which is mainly manifested as a decline in fingertip pinch strength and a decrease in hand dexterity. This trial is registered with Clinical Trial Registry no. ChiCTR1900025358.

中文翻译：

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糖尿病周围神经病变影响老年患者的捏力和手部灵活性

客观。糖尿病周围神经病变 (DPN) 是糖尿病最常见的慢性并发症之一，可导致残疾和生活质量下降。在以往的研究和临床研究中，DPN患者的下肢功能往往是研究的主要对象，很少关注上肢和手部。我们的目标是评估和比较患有 DPN 和没有 DPN 的老年糖尿病患者的手部功能。方法。共有 52 名糖尿病患者登记并接受了手功能评估和电诊断测试。测力计、捏力计、Semmes Weinstein 单丝和 Purdue Pegboard Test (PPT) 用于评估患者的握力、捏力、触觉阈值和手的灵活性。结果. 与非DPN组相比，老年DPN组在惯用手的拇指中指尖捏力和拇指小指尖捏力较差（3.50（2.50, 4.25）vs. 4.50（3.00, 5.00），; 1.50 (1.00, 2.00) 与 2.50 (2.00, 3.00)，); 老年 DPN 组在非惯用手中显示出更差的拇指中指捏力、拇指环指尖捏力和拇指小指尖捏力（3.50 (2.00, 4.50) vs. 4.00 (3.00, 5.00)，; 2.50 (1.25, 3.00) 与 3.00 (2.50, 3.50),; 1.00 (0.75, 2.25) 与 2.50 (2.00, 2.50)，）。老年DPN组在组装的PPT测试中得分低于非DPN组（ 对比 , , ）。 结论。运动功能受限是老年DPN患者主要的手部功能障碍，主要表现为指尖捏力下降和手部灵巧度下降。该试验已在临床试验注册号注册。ChiCTR1900025358。