Background. The overall dietary quality, as well as the dietary total antioxidant capacity (DTAC), deserves central attention in the management of borderline high glucose levels since nonpharmacological strategies are imperative in this regard. Thus, we aimed to investigate the association between prediabetes with dietary quality and DTAC. Methods. A case-control study was conducted on 49 patients with prediabetes and 98 controls. Demographics, anthropometric measures, and fasting blood glucose levels of all participants were obtained. Participants completed a validated 80-item food frequency questionnaire (FFQ). DTAC scores were generated using FFQ data, and Healthy Eating Index-2015 (HEI-2015) was used as a diet quality index. The lowest tertile of HEI-2015 and DTAC was considered as the reference category, and logistic regression was used to estimate the relationship between prediabetes with HEI-215 and DTAC. Results. Mean age and body mass index of participants were 47.42 ± 15.98 years and 27.90 ± 4.96 kg/m². Patients with prediabetes had lower DTAC scores when compared to controls (11.86 ± 5.77 and 17.81 ± 12.08,  = 0.01). There was a significant inverse association between the highest tertile of the DTAC score when compared with the lowest tertile in crude (OR = 0.11; 95% CI: 0.03–0.43), age-adjusted (OR = 0.13; 95% CI: 0.03–0.48), and fully adjusted (OR = 0.09; 95% CI: 0.02–0.53) models. In contrast, there was no difference between HEI-2015 in patients with prediabetes when compared to controls (74.41 ± 8.91 and 74.41 ± 9.35, respectively;  = 0.85). Correspondingly, no difference was observed between the highest tertile of the HEI-2015 score when compared with the lowest tertile in crude (OR = 1.23; 95% CI: 0.53–2.86), age-adjusted (OR = 1.17; 95% CI: 0.48–2.82), and fully adjusted (OR = 1.53; 95% CI: 0.56–4.16) models. Conclusion. This study demonstrates a clear association between prediabetes with less DTAC, but not with HEI-2015.

中文翻译：

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2015 年健康饮食指数和膳食总抗氧化能力作为糖尿病前期的预测因子：病例对照研究


背景。在控制临界高血糖水平时，整体膳食质量以及膳食总抗氧化能力（DTAC）值得重点关注，因为在这方面非药物策略至关重要。因此，我们的目的是研究糖尿病前期与饮食质量和 DTAC 之间的关联。方法。对 49 名糖尿病前期患者和 98 名对照者进行了病例对照研究。获得了所有参与者的人口统计数据、人体测量数据和空腹血糖水平。参与者完成了经过验证的 80 项食物频率调查问卷 (FFQ)。 DTAC 评分是使用 FFQ 数据生成的，健康饮食指数-2015 (HEI-2015) 用作饮食质量指数。 HEI-2015和DTAC的最低三分位数被认为是参考类别，并使用逻辑回归来估计糖尿病前期与HEI-215和DTAC之间的关系。结果。参与者的平均年龄和体重指数分别为47.42±15.98岁和27.90±4.96kg/m ² 。与对照组相比，糖尿病前期患者的 DTAC 评分较低（11.86 ± 5.77 和 17.81 ± 12.08，= 0.01）。与原油中的最低三分位数（OR = 0.11；95% CI：0.03-0.43）、年龄调整（OR = 0.13；95% CI：0.03-）相比，DTAC 评分的最高三分位数之间存在显着的负相关。 0.48）和完全调整（OR = 0.09；95% CI：0.02–0.53）模型。相比之下，与对照组相比，HEI-2015 在糖尿病前期患者中没有差异（分别为 74.41 ± 8.91 和 74.41 ± 9.35；= 0.85）。相应地，与原油中的最低三分位相比，HEI-2015 得分的最高三分位之间没有观察到差异（OR = 1.23； 95% CI：0.53–2.86）、年龄调整（OR = 1.17；95% CI：0.48–2.82）和完全调整（OR = 1.53；95% CI：0.56–4.16）模型。结论。这项研究表明，糖尿病前期与 DTAC 减少之间存在明显关联，但与 HEI-2015 无关。