Maternal depression during gestation is an adverse factor in fetal brain development that manifests in later childhood behavioral problems. Fetal heart rate variability (FHRV) mediated by parasympathetic input is a marker of gestational nervous system development. Biological mediators of adverse effects of maternal depression may involve the mother's corticosteroids; however, links between depression, corticosteroids, and early nervous system development remain inconclusive.

中文翻译：

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母亲皮质类固醇和妊娠期间抑郁症以及胎儿心率变异性降低。


妊娠期间母亲的抑郁是胎儿大脑发育的不利因素，表现为儿童后期的行为问题。由副交感神经输入介导的胎心率变异性（FHRV）是妊娠神经系统发育的标志。母亲抑郁症不良反应的生物介质可能涉及母亲的皮质类固醇；然而，抑郁症、皮质类固醇和早期神经系统发育之间的联系仍然没有定论。