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Statins and Liver Cancer in Cirrhosis: The Most Relevant Questions Are Still Unanswered.
The American Journal of Gastroenterology ( IF 8.0 ) Pub Date : 2021-11-01 , DOI: 10.14309/ajg.0000000000001385
Carlos Moctezuma-Velazquez 1 , Juan G Abraldes 2
Affiliation  

Several observational studies have shown an association between statin use and lower incidence of liver cancer. However, several potential biases limit a causal interpretation that could lead to a recommendation of statin prescription to patients with cirrhosis in the absence of a cardiovascular indication. Ongoing randomized trials will soon provide a clearer picture on the efficacy and safety of statins for preventing liver cancer and other complications of cirrhosis.

中文翻译:

肝硬化中的他汀类药物和肝癌:最相关的问题仍未得到解答。

几项观察性研究表明,他汀类药物的使用与肝癌的低发病率之间存在关联。然而,一些潜在的偏见限制了因果解释,这可能导致在没有心血管适应症的情况下向肝硬化患者推荐他汀类药物处方。正在进行的随机试验将很快就他汀类药物预防肝癌和其他肝硬化并发症的有效性和安全性提供更清晰的图景。
更新日期:2021-07-19
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