A concise and highly efficient procedure has been described for the synthesis of 9-aryl-6-(2-naphthyl)[1,2,4] triazolo[4,3-a][1,8]naphthyridines8 by the oxidation of the corresponding aryl aldehyde1-[3-(2-naphthyl) [1,8]naphthyridin- 2-yl]hydrazones 7 using silica gel supported ferric chloride (SiO2-FeCl3) in solvent-free conditions under microwave irradiation. The desired products are obtained in very good yields and in a state of high purity. The structure of compounds 3-8 have been confirmed by their spectroscopic (IR, 1H NMR and MS) and analytical data. The compounds 8a-j have been screened for their antibacterial activity

中文翻译：

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9-芳基-6-(2-萘基)[1,2,4]三唑并[4,3-a][1,8]萘啶的设计、合成及抗菌活性

已经描述了一种简洁高效的方法，用于通过氧化合成 9-芳基-6-(2-萘基)[1,2,4] 三唑并[4,3-a][1,8]萘啶8相应的芳基醛1-[3-(2-萘基)[1,8]萘啶-2-基]腙 7 使用硅胶负载的氯化铁 (SiO2-FeCl3) 在无溶剂条件下在微波辐射下进行。以非常好的收率和高纯度的状态获得所需的产物。化合物 3-8 的结构已通过其光谱 (IR、1H NMR 和 MS) 和分析数据得到证实。已筛选化合物 8a-j 的抗菌活性