Pharmaceutical compounds in wastewater are currently becoming emerging concern as the utilization of drugs in anthropogenic activities. This research analyzed the effectiveness of pilot-scale vertical subsurface flow constructed wetland (VSSFCW) planted with Scirpus grossus using an aeration system for simultaneous removal of ibuprofen, chemical oxygen demand (COD) and nutrients (NH₃-N, NO₃-N, and PO₄-P) from domestic wastewater. The constructed wetland (CW) platforms (500 L capacity) filled with gravel and sand and planted with native species of S. grossus were used to treat pharmaceutical content in domestic wastewater continuously for 21 days. Three experiments were performed with hydraulic retention time (HRT) of 3, 4 and 5 days. Aeration rates of 0, 1, and 2 L/min were employed for each HRT. The combined effect of HRT, exposure period, and aeration to simultaneously remove ibuprofen, organic materials, and nutrients were examined statistically using Two-way ANOVA and Tukey HSD test. Filtration and adsorption mechanisms of ibuprofen compound by sand medium matrix were proven to occur using solid phase extraction method. The removal efficiency of ibuprofen and COD were dependent on the applied aeration and HRT (p < 0.05). A longer HRT increased the removal efficiency of ibuprofen, while it did not significantly affect the nutrient removal (p ≥ 0.05). The VSSFCW under 2 L/min aeration and HRT of 5 days has removed 99.3% of ibuprofen, 88.2% of COD, 99.1% of ammonia, 72.9% of nitrate-nitrogen, and 83.2% of orthophosphate with effluent successfully met the effluent Standard B set by Malaysian Government. Therefore, the VSSFCW planted with S. grossus becomes a technically feasible method for treating sewage containing pharmaceutical compounds.

随着药物在人为活动中的利用，废水中的药物化合物目前正日益受到关注。该研究分析了中试规模的垂直潜流人工湿地（VSSFCW）种植有效力藨grossus使用曝气系统用于同时去除布洛芬，化学需氧量（COD）和营养物（NH的₃ -N，NO ₃ -N，和 PO ₄ -P) 来自生活废水。人工湿地 (CW) 平台（容量 500 升）充满砾石和沙子，并种植了S.grossus本地物种用于连续处理生活废水中的药物成分 21 天。进行了三个实验，水力停留时间 (HRT) 分别为 3、4 和 5 天。每个 HRT 采用 0、1 和 2 L/min 的通气速率。使用双向 ANOVA 和 Tukey HSD 检验对 HRT、暴露时间和曝气同时去除布洛芬、有机材料和营养物的综合效果进行了统计学检验。固相萃取法证实了布洛芬化合物被砂介质基质过滤和吸附的机理。布洛芬和 COD 的去除效率取决于应用的曝气和 HRT ( p  < 0.05)。较长的HRT提高了布洛芬的去除效率，但对养分去除没有显着影响（p ≥ 0.05)。VSSFCW在2L/min曝气和5天HRT下，布洛芬去除率99.3%，COD去除率88.2%，氨去除率99.1%，硝态氮去除率72.9%，正磷酸盐去除率83.2%，出水成功达到出水标准B马来西亚政府规定。因此，种植与VSSFCW S. grossus变成用于处理含有药物化合物的污水一种技术上可行的方法。