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Adolescent Primary Genital Herpes Simplex Virus Type 1 Infection with Sepsis Secondary to Streptococcus pyogenes Bacteremia
Journal of Pediatric and Adolescent Gynecology ( IF 1.7 ) Pub Date : 2021-07-19 , DOI: 10.1016/j.jpag.2021.07.001
Meredith Holt 1 , Matthew Zerden 2
Affiliation  

Background

Adolescents and young adults are responsible for most new genital herpes virus infections. Historically, primary genital herpes infections were thought to be caused by herpes simplex virus (HSV) type 2, however, recent studies suggest that up to 50% of incident episodes of genital herpes are caused by HSV type 1.

Case

In this case report we present an 18-year-old G1P0010 female who presented with a primary genital HSV type 1 outbreak that resulted in sepsis secondary to Streptococcus pyogenes bacteremia.

Summary and Conclusion

Complications that might arise from HSV include encephalitis, Bell's palsy, aseptic meningitis, hepatitis, pneumonitis, sacral radiculitis, viremia, and superimposed bacterial infections. HSV infections are rarely associated with these complications; however, physicians should be aware of sepsis secondary to bacteremia as a possible complication of primary genital HSV infections when treating immunocompetent adolescents.



中文翻译:

青少年原发性生殖器单纯疱疹病毒 1 型感染继发于化脓性链球菌菌血症的败血症

背景

大多数新的生殖器疱疹病毒感染由青少年和年轻人负责。从历史上看,原发性生殖器疱疹感染被认为是由 2 型单纯疱疹病毒 (HSV) 引起的,但最近的研究表明,高达 50% 的生殖器疱疹事件是由 1 型单纯疱疹病毒引起的。

案件

在本病例报告中,我们介绍了一名 18 岁 G1P0010 女性,她出现原发性生殖器 HSV 1 型暴发,导致继发于化脓性链球菌菌血症的败血症。

总结与结论

HSV 可能引起的并发症包括脑炎、贝尔麻痹、无菌性脑膜炎、肝炎、肺炎、骶神经根炎、病毒血症和叠加细菌感染。HSV 感染很少与这些并发症相关;然而,在治疗免疫功能正常的青少年时,医生应该意识到继发于菌血症的败血症可能是原发性生殖器 HSV 感染的并发症。

更新日期:2021-07-19
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