A wide spectrum of interstitial lung disease (ID) is common and is a well-established manifestation of idiopathic inflammatory myopathies. Yet, till now, the pathogenetic mechanisms are still poorly understood, classification is evolving and prognosis is variable. A refractory and rapidly aggressive form of interstitial lung disease (RPILD) associated with dermatomyositis (DM) with minimal muscle weakness and normal creatine kinase (termed clinically amyopathic DM) is increasingly being recognized, with more incidence in Asians. However, we are not aware of reports of the Arab region. Herein, we present a 38-year-old male with this condition that ended with a fatal outcome despite aggressive therapy, with a review of recent literature.


中文翻译：

---

无肌病性皮肌炎患者致命的快速进展性间质性肺病


广泛的间质性肺病 (ID) 很常见，并且是特发性炎性肌病的公认表现。然而，直到现在，发病机制仍然知之甚少，分类不断发展，预后多变。越来越多地认识到与皮肌炎 (DM) 相关的难治性和快速侵袭性间质性肺病 (RPILD) 具有轻微的肌肉无力和正常的肌酸激酶（称为临床无肌病 DM），在亚洲人中的发病率更高。然而，我们不知道阿拉伯地区的报道。在此，我们介绍了一名患有这种疾病的 38 岁男性，尽管进行了积极的治疗，但仍以致命的结果结束，并回顾了最近的文献。