Background:B7-H6, a newly discovered member of the immunoglobulin superfamily, exerts antitumor effects by binding to NKP30 receptor on natural killer cells; it has important clinical implications. Cell surface ectodomain shedding of B7-H6 generates soluble B7-H6 (sB7-H6), which is highly expressed and serves as a valuable biomarker in multiple tumors, but the clinical significance and diagnostic value of B7-H6 in cervical squamous cell carcinoma (CSCC) remains unclear.

中文翻译：

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B7-H6 作为宫颈鳞状细胞癌的诊断生物标志物

背景： B7-H6是新发现的免疫球蛋白超家族成员，通过与自然杀伤细胞上的NKP30受体结合而发挥抗肿瘤作用；它具有重要的临床意义。B7-H6 的细胞表面胞外域脱落产生可溶性 B7-H6（ sB7-H6），其高表达并作为多种肿瘤中有价值的生物标志物，但B7-H6在宫颈鳞状细胞癌中的临床意义和诊断价值（ CSCC) 仍不清楚。