Herbal extracts have been proven to improve immunity, growth rate and appetite, as well as being antihepatotoxic they are important alternatives to synthetic antibiotics and chemotherapeutics. In this study, Papaveraceae extracts (PE), as alkaloids (quaternary benzophenanthridine and protopine) source were incorporated into the diet of striped catfish, Pangasianodon hypophthalmus, to assess their effects on growth, feed utilisation and digestibility, body composition, product quality and pathogen response. PE was supplemented at 0.7 g/kg (HLPE) and 0.35 g/kg (LLPE) in 30%–35% proteinous diet for 126 days, to determine the effects relative to control group (CC). Growth performance of P. hypophthalmus, measured by weight gain, was improved by 35 % and 25 % in LLPE and HLPE, respectively, compared to CC. The highest protein digestibility, thermal growth coefficient and feed conversion ratio was found in LLPE group. There were no significant differences to proximate composition and colouration of P. hypophthalmus fillets fed PE. After challenging with Aeromonas hydrophila, serum biochemical indices decreased significantly in HLPE treated group. To avoid deleterious effects on P. hypophthalmus fillets and nutritional quality, 0.35 g/kg PE can recommend as safe and economically viable dose for commercial pangasius farming, although curative action against A. hydrophila may require higher dose.

草药提取物已被证明可以提高免疫力、生长速度和食欲，并且具有抗肝毒性，它们是合成抗生素和化疗药物的重要替代品。在这项研究中，罂粟科提取物 (PE) 作为生物碱（季苯并菲啶和普鲁士碱）的来源被加入条纹鲶鱼Pangasianodon hypophthalmus的饮食中，以评估它们对生长、饲料利用和消化率、身体成分、产品质量和病原体的影响回复。在 30%–35% 蛋白质饮食中以 0.7 g/kg (HLPE) 和 0.35 g/kg (LLPE) 补充 PE 126 天，以确定相对于对照组 (CC) 的效果。下眼假单胞菌的生长性能与 CC 相比，LLPE 和 HLPE 的重量增加分别提高了 35% 和 25%。LLPE组的蛋白质消化率、热生长系数和饲料转化率最高。喂食 PE 的下眼假单胞菌鱼片的近似组成和颜色没有显着差异。用嗜水气单胞菌攻击后，HLPE 治疗组的血清生化指标显着下降。为了避免对有害影响P. hypophthalmus鱼片和营养品质，为0.35g / kg的PE可以推荐用于商业鲶耕作安全和经济上可行的剂量，尽管针对治疗作用嗜水可能需要更高的剂量。