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Screening of antidiabetic and antioxidant potential along with phytochemicals of Annona genus: a review
Future Journal of Pharmaceutical Sciences ( IF 3.4 ) Pub Date : 2021-07-19 , DOI: 10.1186/s43094-021-00300-9
Shadman Sakib Chowdhury 1 , Abu Montakim Tareq 1 , Syed Mohammed Tareq 1 , Saifuddin Farhad 1 , Mohammed Abu Sayeed 1
Affiliation  

Annona species can be found in the subtropical and tropical parts of the world. Because of their medicinal capabilities and highly exotic edible fruits, they are one of the most important members of the Annonaceae family. Isoquinolines, pyrimidine-β-carboline alkaloids, lectins, acetogenins, and volatile oils are among the active metabolites found in this genus, all of which have been shown to have anti-diabetic and antioxidant activities. The fundamental objective of this review was to summarize the antidiabetic and antioxidant activity based on reported secondary data from different plants of the genus Annona. These species include Annona cherimola, Annona squamosa, Annona macroprophyllata, Annona muricate, Annona reticulata, Annona carcans, Annona coriacea, Annona cornifolia, and Annona senegalensis. The Annona species investigated had significant antihyperglycemic and antioxidant properties. The available evidence, both in vitro and in vivo, confirms the ability of Annona species to treat diabetes in addition to producing oxidative damage.

中文翻译:

筛选抗糖尿病和抗氧化潜力以及番荔枝属植物化学物质:综述

番荔枝物种可以在世界的亚热带和热带地区找到。由于它们的药用能力和高度奇特的可食用果实,它们是番荔枝科最重要的成员之一。异喹啉、嘧啶-β-咔啉生物碱、凝集素、醋精和挥发油是该属中发现的活性代谢物,所有这些都已被证明具有抗糖尿病和抗氧化活性。本综述的基本目的是根据来自番荔枝属不同植物的报告二级数据总结抗糖尿病和抗氧化活性。这些物种包括番荔枝、番荔枝、番荔枝、番荔枝、番荔枝、番荔枝、番荔枝、番荔枝、番荔枝和塞内加尔番荔枝。所研究的番荔枝属物种具有显着的抗高血糖和抗氧化特性。现有的体外和体内证据证实了番荔枝除了产生氧化损伤外还具有治疗糖尿病的能力。
更新日期:2021-07-19
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