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Advancing health through research: A scoping review of and model for adjunctive psychosocial interventions to improve outcomes for perinatal women with bipolar disorder
Journal of Affective Disorders ( IF 6.6 ) Pub Date : 2021-07-18 , DOI: 10.1016/j.jad.2021.07.024
Ran Friedman 1 , Jennifer Giampaolo 1 , Liselotte Vanhaecke 2 , Robin B Jarrett 1
Affiliation  

Background: We aimed to identify randomized clinical trials (RCTs) which evaluated the efficacy of adjunctive psychosocial interventions to improve outcomes during the perinatal period for women with bipolar disorder (BD).

Methods: We scanned the literature to identify RCTs evaluating the efficacy of adjunctive psychosocial therapies or interventions provided during the perinatal period to women with BD. We searched from 1946 to July 2020 using Embase, Ovid Medline, PsycINFO, and Scopus. We then searched for future, current, and recently completed RCTs described on www.ClinicalTrials.gov.

Results: This scoping review (1946 - July 2020) revealed no published RCTs for this population.

The findings expose an important gap in research and knowledge, as well as a health disparity. Conclusion: We heuristically tied a mechanistic stress reduction model to relevant findings. The initial hypotheses are informed by effective stress reducing psychosocial interventions for: a) people with BD outside the perinatal period and b) perinatal women with major depressive disorder (MDD may improve the health of perinatal women with BD). We hypothesize that the perinatal trajectory of health for women with BD will improve by adding psychosocial interventions or therapies to treatment as usual. We propose maternal stress reduction as a potential mediator/mechanism.

Limitations: Findings reported are limited to the methods of a scoping review. Reproductive status tends to be a missing variable; we highlight the need for its inclusion. Interdisciplinary, collaborative research to improve the treatment outcome for perinatal women with BD is warranted and ripe for advancement.



中文翻译:

通过研究促进健康:辅助心理社会干预措施的范围审查和模型,以改善双相情感障碍围产期妇女的结局

背景:我们旨在确定随机临床试验 (RCT),这些试验评估了辅助心理社会干预对改善双相情感障碍 (BD) 妇女围产期结局的功效。

方法:我们浏览了文献,以确定评估围产期对 BD 妇女提供的辅助心理社会疗法或干预措施的疗效的随机对照试验。我们使用 Embase、Ovid Medline、PsycINFO 和 Scopus 从 1946 年到 2020 年 7 月进行了搜索。然后,我们搜索了 www.ClinicalTrials.gov 上描述的未来、当前和最近完成的 RCT

结果:本次范围界定审查(1946 年至 2020 年 7 月)显示没有针对该人群发表的 RCT。

研究结果揭示了研究和知识方面的重要差距以及健康差距。结论:我们启发式地将机械减压模型与相关发现联系起来。最初的假设是通过有效减少压力的社会心理干预措施得出的:a) 围产期以外的 BD 患者和 b) 患有重度抑郁症的围产期妇女(MDD 可能会改善围产期 BD 妇女的健康)。我们假设,通过像往常一样在治疗中加入社会心理干预或疗法,BD 女性的围产期健康轨迹将会得到改善。我们建议将减轻孕产妇压力作为潜在的中介/机制。

局限性:报告的结果仅限于范围界定审查的方法。生殖状态往往是一个缺失的变量;我们强调需要将其纳入。改善围产期 BD 妇女治疗结果的跨学科合作研究是有必要的,并且已经成熟。

更新日期:2021-07-28
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