We explore the influence of charge state on gas-phase chemistry at room temperature (here referred to as “charge state chemistry”). Illustrative examples are drawn largely from the author's own research, but also from the work of Paul Kebarle and others. Emphasis is given to reactions of atoms and atomic ions, singly and multiply charged cations of C₆₀, and multiply-charged anions of selected deprotonated oligodeoxynucleotides. Large and intriguing changes in chemical reactivity are observed with changes in the charge state of the reactant ion. Electrostatic interactions between reactants and between products, including Coulomb repulsion between product ions, can override thermodynamics and so be decisive in determining chemical reactivity. Notable and characteristic features of both atomic and molecular charge state chemistry are summarized in closing.

我们探讨了室温下电荷态对气相化学（此处称为“电荷态化学”）的影响。说明性示例主要来自作者自己的研究，但也来自 Paul Kebarle 和其他人的工作。重点是原子和原子离子的反应，C _{60 的}单电荷和多电荷阳离子，以及选定的去质子化寡脱氧核苷酸的多电荷阴离子。随着反应离子电荷状态的变化，观察到化学反应性的巨大而有趣的变化。反应物之间和产物之间的静电相互作用，包括产物离子之间的库仑排斥，可以超越热力学，因此在确定化学反应性方面起决定性作用。最后总结了原子和分子电荷态化学的显着特征。