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Platelet Phagocytosis via P-selectin Glycoprotein Ligand 1 and Accumulation of Microparticles in Systemic Sclerosis
Arthritis & Rheumatology ( IF 11.4 ) Pub Date : 2021-07-19 , DOI: 10.1002/art.41926 Angelo A Manfredi 1 , Giuseppe A Ramirez 1 , Cosmo Godino 1 , Annalisa Capobianco 1 , Antonella Monno 1 , Stefano Franchini 1 , Enrico Tombetti 1 , Sara Corradetti 1 , Jörg H W Distler 2 , Marco E Bianchi 1 , Patrizia Rovere-Querini 1 , Norma Maugeri 1
Arthritis & Rheumatology ( IF 11.4 ) Pub Date : 2021-07-19 , DOI: 10.1002/art.41926 Angelo A Manfredi 1 , Giuseppe A Ramirez 1 , Cosmo Godino 1 , Annalisa Capobianco 1 , Antonella Monno 1 , Stefano Franchini 1 , Enrico Tombetti 1 , Sara Corradetti 1 , Jörg H W Distler 2 , Marco E Bianchi 1 , Patrizia Rovere-Querini 1 , Norma Maugeri 1
Affiliation
It is unclear why activated platelets and platelet-derived microparticles (MPs) accumulate in the blood of patients with systemic sclerosis (SSc). This study was undertaken to investigate whether defective phagocytosis might contribute to MP accumulation in the blood of patients with SSc.
中文翻译：
P-选择素糖蛋白配体 1 的血小板吞噬作用和系统性硬化症中微粒的积累
目前尚不清楚为什么活化的血小板和血小板衍生微粒 (MPs) 会在系统性硬化症 (SSc) 患者的血液中积聚。本研究旨在调查有缺陷的吞噬功能是否可能导致 SSc 患者血液中 MP 的积累。
更新日期：2021-07-19
中文翻译：
P-选择素糖蛋白配体 1 的血小板吞噬作用和系统性硬化症中微粒的积累
目前尚不清楚为什么活化的血小板和血小板衍生微粒 (MPs) 会在系统性硬化症 (SSc) 患者的血液中积聚。本研究旨在调查有缺陷的吞噬功能是否可能导致 SSc 患者血液中 MP 的积累。
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