MicroRNAs play an important role in microbiota-host crosstalk. In this study, we compared microRNA expression in whole colons of specific pathogen-free mice and germ-free mice. Forty-eight microRNAs were differentially expressed by more than 2-fold. Gene ontology analysis of the predicted mRNA targets revealed that the majority of the most significant gene ontology terms were related to GTPases and nerves.

中文翻译：

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特定无病原体小鼠和无菌小鼠结肠中 microRNA 表达谱的比较分析。

MicroRNA 在微生物群-宿主串扰中发挥着重要作用。在这项研究中，我们比较了特定无病原体小鼠和无菌小鼠的整个结肠中的 microRNA 表达。48 个 microRNA 差异表达超过 2 倍。预测的 mRNA 目标的基因本体分析表明，大多数最重要的基因本体术语与 GTP 酶和神经有关。