Trypanosoma cruzi Exploits E- and P-Selectins to Migrate Across Endothelial Cells and Extracellular Matrix Proteins,Infection and Immunity

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Trypanosoma cruzi Exploits E- and P-Selectins to Migrate Across Endothelial Cells and Extracellular Matrix Proteins
Infection and Immunity ( IF 2.9 ) Pub Date : 2021-07-06 , DOI: 10.1128/iai.00178-21
Smaro Panagiotidou _{1,

2} , Marina Anastasiou _{3,

4} , Pilar Alcaide _{3,

5} , Mercio A Perrin _{1,

2,

5}

Affiliation

The Chagas disease parasite Trypanosoma cruzi must extravasate to home in on susceptible cells residing in most tissues. It remains unknown how T. cruzi undertakes this crucial step of its life cycle. We hypothesized that the pathogen exploits the ...

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