Structural Basis and Function of the N Terminus of SARS-CoV-2 Nonstructural Protein 1,Microbiology Spectrum

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Structural Basis and Function of the N Terminus of SARS-CoV-2 Nonstructural Protein 1
Microbiology Spectrum Pub Date : 2021-06-16 , DOI: 10.1128/spectrum.00169-21
Kaitao Zhao ₁ , Zunhui Ke ₂ , Hongbing Hu ₂ , Yahui Liu ₃ , Aixin Li ₁ , Rong Hua ₁ , Fangteng Guo ₁ , Junfeng Xiao ₃ , Yu Zhang ₄ , Ling Duan ₂ , Xin-Fu Yan ₅ , Yong-Gui Gao ₅ , Bing Liu _{6,

7} , Yuchen Xia ₁ , Yan Li _{3,

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Affiliation

Nonstructural protein 1 (Nsp1) of severe acute respiratory syndrome coronaviruses (SARS-CoVs) is an important pathogenic factor that inhibits host protein translation by means of its C terminus. However, its N-terminal function remains elusive.

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