Osteoporosis, a disease characterized by low bone mass and alterations of bone microarchitecture, leading to an increased risk for fragility fractures and, eventually, to fracture; is associated with an excess of mortality, a decrease in quality of life, and co-morbidities. Bone mineral density (BMD), measured by dual X-ray absorptiometry (DXA), has been the gold standard for the diagnosis of osteoporosis. Trabecular bone score (TBS), a textural analysis of the lumbar spine DXA images, is an index of bone microarchitecture. TBS has been robustly shown to predict fractures independently of BMD. In this review, while reporting also results on BMD, we mainly focus on the TBS role in the assessment of bone health in endocrine disorders known to be reflected in bone.

骨质疏松症，一种以骨量低和骨微结构改变为特征的疾病，导致脆性骨折并最终导致骨折的风险增加；与死亡率过高、生活质量下降和合并症有关。通过双 X 射线吸收测定法 (DXA) 测量的骨矿物质密度 (BMD) 一直是诊断骨质疏松症的金标准。骨小梁评分（TBS）是腰椎 DXA 图像的纹理分析，是骨微结构的指标。 TBS 已被证明可以独立于 BMD 预测骨折。在这篇综述中，虽然也报告了 BMD 的结果，但我们主要关注 TBS 在评估已知反映在骨骼中的内分泌紊乱中的骨骼健康中的作用。