当前位置: X-MOL 学术Biomed. Phys. Eng. Express › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
PAGAT gel dosimetry for everyone: gel production, measurement and evaluation
Biomedical Physics & Engineering Express ( IF 1.3 ) Pub Date : 2021-07-21 , DOI: 10.1088/2057-1976/ac12a5
A Elter 1, 2, 3 , S Dorsch 1, 3 , S Thomas 4 , C M Hentschke 4 , R O Floca 3, 4 , A Runz 1, 3 , C P Karger 1, 3 , P Mann 1, 3
Affiliation  

Polymer gel (PG) dosimetry is a valuable tool to measure complex dose distributions in 3D with a high spatial resolution. However, due to complex protocols that need to be followed for in-house produced PGs and the high costs of commercially available gels, PG gels are only rarely applied in quality assurance procedures worldwide. In this work, we provide an introduction to perform highly standardized dosimetric PG experiments using PAGAT (PolyAcrylamide Gelatine gel fabricated at ATmospheric conditions) dosimetry gel. PAGAT gel can be produced at atmospheric conditions, at low costs and is evaluated using magnetic resonance imaging (MRI). The conduction of PG experiments is described in great detail including the gel production, treatment planning, irradiation, MRI evaluation and post-processing procedure. Furthermore, a plugin in an open source image processing tool for post-processing is provided free of charge that allows a standardized and reproducible analysis of PG experiments.



中文翻译:

适合所有人的 PAGAT 凝胶剂量测定:凝胶生产、测量和评估

聚合物凝胶 (PG) 剂量测定法是一种有价值的工具,可以以高空间分辨率测量 3D 中的复杂剂量分布。然而,由于内部生产的 PG 需要遵循复杂的协议以及市售凝胶的高成本,PG 凝胶在全球的质量保证程序中很少应用。在这项工作中,我们介绍了使用 PAGAT(在大气条件下制造的聚丙烯酰胺明胶凝胶)剂量测定凝胶进行高度标准化的剂量测定 PG 实验。PAGAT 凝胶可以在大气条件下以低成本生产,并使用磁共振成像 (MRI) 进行评估。详细描述了 PG 实验的实施,包括凝胶生产、治疗计划、照射、MRI 评估和后处理程序。此外,

更新日期:2021-07-21
down
wechat
bug