Recently, an electrical stimulation of the paralyzed muscle, as a potential therapy for restoring function of a denervated muscle system, has been debated as an innovative treatment in the management of patients with laryngeal paralysis. Numerous studies in acute and chronic animal models have demonstrated that electrical stimulation of the paralyzed posterior cricoarytenoideus muscle (PCA) offers an approach to induce vocal fold abduction and restore ventilation through the glottis. The study aims to test applicability of the controlled opening of the rima glottides via direct electrical stimulation of the posterior cricoarytenoideus muscle. We developed for this purpose a novel instrument system for the controlled larynx nerve stimulation. An acute experiment on the 4 years old pig showed effectiveness of the engineered stimulator. The controlled opening of rima glottidis of both posterior cricoarytenoid muscles and afterwards of both PCA muscle contraction were observed as a result of the electrical stimulation with the applied current in the range of 0.1–3 mA and pulse width of 1 ms and 10 ms. Performed research indicates a large potential of the novel nerve stimulator for the human larynx stimulation.

中文翻译：

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具有肌电图采集功能和无线连接功能的喉部神经刺激器的功能评估


最近，麻痹肌肉的电刺激作为恢复失神经肌肉系统功能的潜在疗法，一直被争论为治疗喉麻痹患者的创新疗法。对急性和慢性动物模型的大量研究表明，对瘫痪的环杓后肌（PCA）进行电刺激提供了一种诱导声带外展并恢复声门通气的方法。该研究旨在测试通过直接电刺激后环杓肌来控制裂孔缘打开的适用性。为此，我们开发了一种用于受控喉神经刺激的新型仪器系统。对 4 岁猪进行的急性实验显示了工程刺激器的有效性。通过施加电流范围为 0.1-3 mA、脉冲宽度为 1 ms 和 10 ms 的电刺激，观察到两个环杓后肌的声门受控打开以及随后的两个 PCA 肌肉收缩。进行的研究表明新型神经刺激器在人类喉部刺激方面具有巨大的潜力。